Document Type
Article
Original Publication Date
2010
Journal/Book/Conference Title
PLOS Comput Biol
Volume
6
DOI of Original Publication
10.1371/journal.pcbi.1000786
Date of Submission
November 2014
Abstract
This article describes the typical stages in the analysis of microarray data for non-specialist researchers in systems biology and medicine. Particular attention is paid to significant data analysis issues that are commonly encountered among practitioners, some of which need wider airing. The issues addressed include experimental design, quality assessment, normalization, and summarization of multiple-probe data. This article is based on the ISMB 2008 tutorial on microarray data analysis. An expanded version of the material in this article and the slides from the tutorial can be found at http://www.people.vcu.edu/~mreimers/OGMDA/index.html.
Rights
Copyright: © 2010 Mark Reimers. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Is Part Of
VCU Biostatistics Publications
Comments
Originally Published at http://dx.doi.org/10.1371/journal.pcbi.1000786