Defense Date

1980

Document Type

Thesis

Degree Name

Master of Science

Department

Biology

First Advisor

Loren G. Martin

Abstract

Clinical and experimental data suggest that humans and some animals are protected from acute myocardial infarction by estrogen. There has been much speculation of the exact role which estrogen plays in the circulation. The mechanism of this hormonally related protection is unclear.

In the present study the chronic effects of estradiol benzoate on coronary blood flow in adult female rats were studied. Female control rats, castrates and castrates receiving estrogen for a period of 16 weeks were used. In vivo tracer microsphere studies of myocardial blood flow allowed the quantification of the effects of estrogen on coronary circulation. Results of this work demonstrated that levels of estrogen significantly influence blood flow in ventricular myocardium.

Rights

© The Author

Is Part Of

VCU University Archives

Is Part Of

VCU Theses and Dissertations

Date of Submission

6-28-2016

Included in

Biology Commons

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