Defense Date

1997

Document Type

Thesis

Degree Name

Master of Science

Department

Biostatistics

First Advisor

Sung C. Choi

Abstract

This thesis concerns the estimation of extreme quantiles on a dose-response curve. It focuses on the Robbins-Monro and up-and-down procedures. Simulation studies run in search of the LD15 and LD30 using a variety of methods suggest that the Robbins-Monro procedure is optimal in terms of Monte Carlo MSE and bias. The up-and-down procedure's performance differs in many cases only slightly from that of the Robbins-Monro process, therefore indicating its value as a practical alternative to the Robbins-Monro process for extreme-quantile estimation.

Rights

© The Author

Is Part Of

VCU University Archives

Is Part Of

VCU Theses and Dissertations

Date of Submission

7-20-2016

Included in

Life Sciences Commons

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