Solubilization and Partial Characterization of an Activity Regulating Complement Activation from Membranes of Raji and Tonsil Cells

Author

Patricia L. CarlsonFollow

DOI

https://doi.org/10.25772/ZDXP-8E55

Defense Date

1981

Document Type

Thesis

Degree Name

Doctor of Philosophy

Department

Microbiology & Immunology

First Advisor

Shaun Ruddy

Abstract

Complement is one of the major innate nonspecific mechanisms for host defense in serum. More than a dozen proteins have been isolated from serum which have a function in either the activation or regulation of complement action. Complement is similar to the coagulation sequence in that it comprises a number of precursor proenzymes in plasma that are sequentially cleaved to generate biologically and enzymatically active proteins.

Rights

© The Author

Is Part Of

VCU University Archives

Is Part Of

VCU Theses and Dissertations

Date of Submission

7-26-2016