Author ORCID Identifier

0000-0002-5387-7565

Defense Date

2017

Document Type

Thesis

Degree Name

Master of Science

Department

Mathematical Sciences

First Advisor

Rebecca Segal

Second Advisor

Laura Ellwein-Fix

Third Advisor

Rebecca Heise

Abstract

Mathematical Biology has found recent success applying Computational Fluid Dynamics (CFD) to model airflow in the human lung. Detailed modeling of flow patterns in the alveoli, where the oxygen-carbon dioxide gas exchange occurs, has provided data that is useful in treating illnesses and designing drug-delivery systems. Unfortunately, many CFD software packages have high licensing fees that are out of reach for independent researchers. This thesis uses three open-source software packages, Gmsh, OpenFOAM, and ParaView, to design a mesh, create a simulation, and visualize the results of an idealized terminal alveolar sac model. This model successfully demonstrates that OpenFOAM can be used to model airflow in the acinar region of the lung under biologically relevant conditions.

Rights

© The Author

Is Part Of

VCU University Archives

Is Part Of

VCU Theses and Dissertations

Date of Submission

8-9-2017