Document Type
Article
Original Publication Date
2020
Journal/Book/Conference Title
PeerJ
Volume
8:e9272
First Page
1
Last Page
22
DOI of Original Publication
10.7717/peerj.9272
Date of Submission
August 2020
Abstract
Monkeypox (MPX) is a zoonotic disease similar to smallpox. Its fatality rate is about 11% and it is endemic to the Central and West African countries. In this paper, we analyze a compartmental model of MPX dynamics. Our goal is to see whether MPX can be controlled and eradicated by voluntary vaccinations. We show that there are three equilibria—disease free, fully endemic and previously neglected semi-endemic (with disease existing only among humans). The existence of semi-endemic equilibrium has severe implications should the MPX virus mutate to increased viral fitness in humans. We find that MPX is controllable and can be eradicated in a semi-endemic equilibrium by vaccination. However, in a fully endemic equilibrium, MPX cannot be eradicated by vaccination alone.
Rights
© 2020 Bankuru et al. Licence This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed.
Is Part Of
VCU Mathematics and Applied Mathematics Publications
Comments
Originally published at https://doi.org/10.7717/peerj.9272.
Funded in part by the VCU Libraries Open Access Publishing Fund.