Orginal Publication Date
MCV/Q, Medical College of Virginia Quarterly
I will begin by telling a little about the development of chronic dialysis. In 1959 we were working on a system to prevent uremia in acute renal failure. We were trying to develop a system to which we could "hook" the patient for as long as a week, so that we would exactly mimic his normal kidney function during the period of acute renal failure, and make his prognosis that of a patient who had kidneys. The system worked reasonably well. We had to make a lot of modifications, such as using a Skeggs-Leonard dialyzer with low resistance. We used a large deep freeze as a dialysate reservoir because we could not afford to change the bath ever few hours. The patients was on continuously. We had to cool the external circuit to control clotting problems and infection. We actually had patients on this system for as long as two weeks. It was important to us that we had this system in operation at the time we first devised the cannulas.
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