Orginal Publication Date
MCV/Q, Medical College of Virginia Quarterly
The following investigation had been conducted to evaluate lens epithelial cells in vitro as a potential suitable model for future studies of chronic low dose ionizing radiation effects on this cell type in vitro. Since there is a great range of dose requirements to produce in vivo radiation cataract in man, monkeys, and rabbits, and an equally wide range in time from radiation exposure until the first minimal lens changes can be biomicroscopically detected, it may be assumed that in vitro comparison of cells derived from these three species may provide some explanation for the in vivo differences.
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