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Our findings indicate that treatment with poly[I:C] in the 6 week SuHxmodel reduced the overgrowth of EPCs marked with c-kit found in the pulmonary vasculature.
Flow cytometry indicate that treatment with poly[I:C] in the 6 week model also decreases the overall number of c-kit+ and VEGFR+ cells in SuHxmodel tissue.
These findings suggest that poly[I:C] may be more useful as a therapeutic rather than preventative measure.
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VCU School of Medicine MD Student Summer Research Fellowship Program Posters