Publications from the Department of Pharmacology and Toxicology, Virginia Commonwealth University.

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Submissions from 2017

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Multiple blood-brain barrier transport mechanisms limit bumetanide accumulation, and therapeutic potential, in the mammalian brain, Kerstin Römermann, Maren Fedrowitz, Philip Hampel, Edith Kaczmarek, Kathrin Töllner, Thomas Erker, Douglas H. Sweet, and Wolfgang Löscher

Submissions from 2016

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Effects of 7-day repeated treatment with the 5-HT2A inverse agonist/antagonist pimavanserin on methamphetamine vs. food choice in male rhesus monkeys, Matthew L. Banks L. Banks

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Development of a translational model to screen medications for cocaine use disorder I: Choice between cocaine and food in rhesus monkeys, Amy R. Johnson

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Identification of the Metabolic Enzyme Involved Morusin Metabolism and Characterization of Its Metabolites by Ultraperformance Liquid Chromatogaphy Quadrupole Time-of-Flight Mass Spectrometry (UPLC/Q-TOF-MS/MS), Xianbao Shi, Brianna Mackie, Gang Zhang, Shuman Yang, Yonggui Song, Dan Su, Yali Liu, and Lina Shan

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Time-Course Analysis of Brain Regional Expression Network Responses to Chronic Intermittent Ethanol and Withdrawal: Implications for Mechanisms Underlying Excessive Ethanol Consumption, Maren L. Smith, Marcelo F. Lopez, Kellie Archer, Aaron R. Wolen, Howard C. Becker, and Michael F. Miles

Submissions from 2015

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Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?, Justine M. Abais, Min Xia, Yang Zhang, Krishna M. Boini, and Pin-Lan Li

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Effects of Menthol on Nicotine Pharmacokinetic, Pharmacology and Dependence in Mice, Sharki D. Alsharari, Justin R. King, Jacob C. Nordman, Pretal P. Muldoon, Asti Jackson, Andy Z. X. Zhu, Rachel F. Tyndale, Nadine Kabbani, and M. Imad Damaj

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Adipose-derived mesenchymal stem cells improve glucose homeostasis in high-fat diet-induced obese mice, Mingjun Cao, Qingjie Pan, Huanshen Dong, Xinxu Yuan, Yang Li, Zhen Sun, Xiao Dong, and Hongjun Wang

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Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure, Seth M. Dever, Myosotys Rodriguez, Jessica Lapierre, Blair N. Costin, and Nazira El-Hage

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Stem Cell Conditioned Culture Media Attenuated Albumin-Induced Epithelial– Mesenchymal Transition in Renal Tubular Cells, Junping Hu, Qing Zhu, Pin-Lan Li, Weili Wang, Fan Yi, and Ningjun Li

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Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action, Andreu Viader, Jacqueline L. Blankman, Peng Zhong, Xiaojie Liu, Joel E. Scholsburg, Christopher M. Joslyn, Qing-Song Liu, Aaron J. Tomarchio, Aron H. Lichtman, Dana E. Selley, Laura J. Sim-Selley, and Benjamin F. Cravatt

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Contribution of Nrf2 to Atherogenic Phenotype Switching of Coronary Arterial Smooth Muscle Cells Lacking CD38 Gene, Ming Xu, Xiao-Xue Li, Lei Wang, Mi Wang, Yang Zhang, and Pin-Lan Li

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Concentration-Dependent Diversification Effects of Free Cholesterol Loading on Macrophage Viability and Polarization, Xiaoyang Xu, Aolin Zhang, Ningjun Li, Pin-Lan Li, and Fan Zhang

Submissions from 2014

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Contrasting influences of Drosophila white/mini-white on ethanol sensitivity in two different behavioral assays, Robin F. Chan, Carol Atkinson Lewellyn, Jacqueline M. DeLoyht, Kristyn Sennett, Scarlett Coffman, Matthew Hewitt, Jill C. Bettinger, John M. Warrick, and Mike Grotewiel

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Activation of Nlrp3 Inflammasomes Enhances Macrophage Lipid-Deposition and Migration: Implication of a Novel Role of Inflammasome in Atherogenesis, Xiang Li, Yang Zhang, Min Xia, Erich Gulbins, Krishna M. Boini, and Pin-Lan Li

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Specific Localization of β-Arrestin2 in Myenteric Plexus of Mouse Gastrointestinal Tract, Hercules T. Maguma, Dipanjana D. De, Sukhada Bhave, William L. Dewey, and Hamid I. Akbarali

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The Omega-3 Fatty Acid Eicosapentaenoic Acid Is Required for Normal Alcohol Response Behaviors in C. elegans, Richard C. Raabe, Laura D. Mathies, Andrew G. Davies, and Jill C. Bettinger

Submissions from 2013

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Cannabinoid CB2 Receptors Regulate Central Sensitization and Pain Responses Associated with Osteoarthritis of the Knee Joint, James J. Burston, David R. Sagar, Pin Shao, Mingfeng Bai, Emma King, Louis Brailsford, Jenna M. Turner, Gareth J. Hathway, Andrew J. Bennett, David A. Walsh, David A. Kendall, Aron H. Lichtman, and Victoria Chapman

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Ethanol Regulation of Serum Glucocorticoid Kinase 1 Expression in DBA2/J Mouse Prefrontal Cortex, Blair N. Costin, Seth M. Dever, and Michael F. Miles

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Fyn-Dependent Gene Networks in Acute Ethanol Sensitivity, Sean P. Farris and Michael F. Miles

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Contribution of NADPH Oxidase to Membrane CD38 Internalization and Activation in Coronary Arterial Myocytes, Ming Xu, Xiao-Xue Li, Joseph K. Ritter, Justine M. Abais, Yang Zhang, and Pin-Lan Li

Submissions from 2012

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MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys, Mario D. Aceto, Louis S. Harris, S. Stevens Negus, Matthew L. Banks, Larry D. Hughes, Eyup Akgun, and Philip S. Portoghese

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Low Dose Nicotine and Antagonism of β2 Subunit Containing Nicotinic Acetylcholine Receptors Have Similar Effects on Affective Behavior in Mice, Shawn M. Anderson and Darlene H. Brunzell

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Preclinical Determinants of Drug Choice under Concurrent Schedules of Drug Self-Administration, Matthew L. Banks and S. Stevens Negus

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Lipid Environment Modulates the Development of Acute Tolerance to Ethanol in Caenorhabditis elegans, Jill C. Bettinger, Kapo Leung, Mia H. Bolling, Andrew D. Goldsmith, and Andrew G. Davies