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Abstract

Two chemotherapeutic drugs were studied; one of them is Cisplatin that is currently used to fight cancer and the other is Triplatin (BBR3464) that was developed by Dr. Farrell. Cisplatin was synthesized and many different experiments were conducted such as: Recrystallization, Infrared Spectroscopy, UV-VIS, Melting Point, and Fluorescence experiment. After synthesizing the drug, it was tested in biology lab; we tested the effects of the drug on ovary cancer cells and its ability to kill cancer cells. A Cisplatin MTT ASSAY experiment was done and another MTT for Triplatin was done. Results from both of the experiments were compared and it was concluded that Triplatin is able to kill cancer cells more effectively and at lower concentrations than Cisplatin.

Publication Date

2014

Subject Major(s)

Chemistry and Biology

Current Academic Year

Sophomore

Faculty Advisor/Mentor

Nicholas Farrell

Sponsorship

Virginia Commonwealth University. Undergraduate Research Opportunities Program

Is Part Of

VCU Undergraduate Research Posters

Rights

© The Author(s)

Synthesis of Cisplatin & biological testing of the complex, compared to Triplatin (BBR3464)

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