Defense Date


Document Type


Degree Name

Master of Science



First Advisor

Eser Tüfekçi


Enamel demineralization is a concern in orthodontic patients with poor oral hygiene. To curtail this problem, amorphous calcium phosphate (ACP) containing adhesives have been developed. The purpose of this in vitro study was to evaluate the cariostatic potential of an ACP containing orthodontic bonding agent adjacent to brackets. Sixty human molars were randomly distributed into: ACP adhesive, resin modified glass ionomer cement (RMGIC), and conventional composite resin groups (N=20 each). Brackets were bonded following the manufacturer’s instructions. Tooth enamel through a 2mm window around the brackets was cycled in demineralization (6 hrs) and remineralization (18 hrs) solutions. After 14 days, teeth embedded in resin and were sectioned. Knoop indentations were performed to determine enamel hardness. There were no statistically significant differences between the control and experimental groups. However, both Fuji Ortho LC (RMGIC), and Aegis Ortho (ACP) showed a trend toward a reduction in demineralization. In addition, it was also shown that the initial acid etching of the enamel significantly reduces enamel hardness.


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Is Part Of

VCU University Archives

Is Part Of

VCU Theses and Dissertations

Date of Submission

May 2010