Title

Putting the Pieces Together: Experimentally Evaluating Alternative RNA Splicing Variants [online video]

Document Type

Presentation

Original Publication Date

2019

Streaming Media

Comments

Presented by Melissa Hale, Pd.D. on November 4, 2019

Part of "How-to Talks by Postdocs," a series of instructional brown-bag lunch talks for the general VCU health sciences community taught by postdocs. For more information, visit https://rampages.us/howtotalks

Date of Submission

April 2020

Abstract

Alternative splicing (AS) results in different protein products from the same genetic code. How does the cell choose what to do? These choices are critical for proper gene expression. In fact, it has been estimated that AS is dysregulated in over half of all human genetic diseases. This talk will cover how to design and execute experiments to evaluate changes in AS patterns of target genes -- globally with next-generation sequencing like RNASeq and in a targeted manner with techniques such as RT-PCR.

Rights

© The Author

Is Part Of

VCU How-To Talks by Postdocs

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