MCV/Q, Medical College of Virginia Quarterly
Orginal Publication Date
1977
Journal Title
MCV/Q, Medical College of Virginia Quarterly
Volume
13
Issue
4
First Page
179
Last Page
182
Abstract
Ring chromosomes originate in the simultaneous occurrence of two breaks at opposite ends of the chromosome and the subsequent reuniting of the free ends to form a ring. They may be compatible with normal life, as only a fractional loss of genetic material has occurred, or they may lead to spontaneous abortion or to an offspring with severe physical and mental handicap attributable to significant genetic alterations.
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