Orginal Publication Date
MCV/Q, Medical College of Virginia Quarterly
Acute renal failure following severe trauma, shock, transfusion reactions, poisoning, and sepsis is characterized by prolonged oliguria, increasing azotemia, isosthenuria, and a sodium concentration of 40-90 mEq/L. Despite the availability of intensive medical and surgical care, potent antibiotics, and dialysis, this syndrome still carries a mortality rate of approximately 50% and once established cannot be reversed by any known medical regimen. It is, however, often preventable, and the purpose of this paper is to evaluate the efficacy of the various prophylactic measures currently in vogue.
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