Orginal Publication Date
MCV/Q, Medical College of Virginia Quarterly
Our clinical experience and the experience of others seems to indicate that pituitary ablation can induce a significant beneficial effect on the course of diabetic retinitis, even in advanced stages. We have no strict criteria for the selection of patients. When surgical hypophysectomy is being done, the major restriction is whether the patient has a fair chance of getting through the procedure without great risk of death or serious complication. With yttrium-implant hypophysectomy, the risk of death from the procedure itself has been practically eliminated. The morbidity would be much less if the rhinorrhea and the threat of meningitis could be eliminated completely. From our experience, the procedure appears to be futile in patients with severe retinitis proliferans with very little vision left. Where there is useful vision left, even 20/100 or less in one eye, where there appears to be a chance of reversibility, we have seen striking improvement lasting for several years.
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