Yuzhang Zhu, The First Hospital of China Medical University
Hongni Zhang, The First Hospital of China Medical University
Shenxun Shi, Huashan Hospital of Fudan University
Jingfang Gao, Chinese Traditional Hospital of Zhejiang
Youhui Li, Hospital of Zhengzhou University
Ming Tao, Xinhua Hospital of Zhejiang Province
Kerang Zhang, Hospital of Shanxi Medical University
Xumei Wang, ShengJing Hospital of China Medical University
Chengge Gao, Hospital of Medical College of Xian Jiaotong University
Lijun Yang, Jilin Brain Hospital
Kan Li, Mental Hospital of Jiangxi Province
Jiangguo Shi, Xian Mental Health Center
Gang Wang, Capital Medical University
Lanfen Liu, Shandong Mental Health Center
Jinbei Zhang, Sun Yat-sen University
Bo Du, Hebei Mental Health Center
Guoqing Jiang, Chongqing Mental Health Center
Jianhua Shen, Tianjin Anding Hospital
Zhen Zhang, Jiangsu University
Wei Liang, Psychiatric Hospital of Henan Province
Jing Sun, Nanjing Brain Hospital
Jian Hu, Harbin Medical University
Tiebang Liu, Shenzhen Kangning Hospital
Xueyi Wang, The First Hospital of Hebei Medical University
Guodong Miao, Guangzhou Brain Hospital Guangzhou
Huaqing Meng, Hospital of Chongqing Medical University
Yi Li, Dalian No. 7 Hospital
Chunmei Hu, Bo. 3 Hospital of Heilongjiang Province
Yi Li, Wuhan Mental Health Center
Guoping Huang, Sichuan Mental Health Center
Gongying Li, Mental Health Institute of Jining Medical College
Baowei Ha, Liaocheng No. 4 Hospital
Hong Deng, Mental Health Center of West China Hospital of Sichuan University
Qiyi Mei, Suzhou Guangji Hospital
Hui Zhong, Anhui Mental Health Center
Shugui Gao, Ningbo Kang Ning Hospital
Hong Sang, Changchun Mental Hospital
Yutang Zhang, No. 2 Hospital of Lanzhou University
Xiang Fang, Fuzhou Psychiatric Hospital
Fengyu Yu, Harbin No. 1 Special Hospital
Donglin Yang, Jining Psychiatric Hospital
Tieqiao Liu, No. 2 Xiangya Hospital of Zhongnan University
Yunchun Chen, Xijing Hospital of No. 4 Military Medical University
Xiaohong Hong, Mental Health Center of Shantou University
Wenyuan Wu, Tongji University Hospital
Guibing Chen, Huaian No. 3 Hospital
Min Cai, Huzhou No. 3 Hospital
Yan Song, Mudanjiang Psychiatric Hospital of Heilongjiang Province
Jiyang Pan, No. 1 Hospital of Jinan University
Jicheng Dong, Qingdao Mental Health Center
Runde Pan, Guangxi Longquanshan Hospital
Wei Zhang, Daqing No. 3 Hospital of Heilongjiang Province
Zhenming Shen, Tangshan No. 5 Hospital
Zhengrong Liu, Anshan Psychiatric Rehabilitation Hospital
Danhua Gu, Weihai Mental Health Center
Xiaoping Wang, Renmin Hospital of Wuhan University
Xiaojuan Liu, Tianjin First Center Hospital
Qiwen Zhang, Hainan Anning Hospital
Yihan Li, Wellcome Trust Centre for Human Genetics
Yiping Chen, Clinical Trial Service Unit
Kenneth S. Kendler, Virginia Commonwealth UniversityFollow
Jonathan Flint, Wellcome Trust Centre for Human Genetics
Ying Liu, The First Hospital of China Medical University

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November 2014


The relationship between suicidality and major depression is complex. Socio- demography, clinical features, comorbidity, clinical symptoms, and stressful life events are important factors influencing suicide in major depression, but these are not well defined. Thus, the aim of the present study was to assess the associations between the above-mentioned factors and suicide ideation, suicide plan, and suicide attempt in 6008 Han Chinese women with recurrent major depression (MD). Patients with any suicidality had significantly more MD symptoms, a significantly greater number of stressful life events, a positive family history of MD, a greater number of episodes, a significant experience of melancholia, and earlier age of onset. Comorbidity with dysthymia, generalized anxiety disorder (GAD), social phobia, and animal phobia was seen in suicidal patients. The present findings indicate that specific factors act to increase the likelihood of suicide in MD. Our results may help improve the clinical assessment of suicide risk in depressed patients, especially for women.


Copyright: © 2013 Zhu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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VCU Psychiatry Publications