Original Publication Date
The New England Journal of Medicine
DOI of Original Publication
Date of Submission
We tested serial bone-marrow samples from 47 adults with acute myeloblastic leukemia in remission for reactivity with heteroantiserums to leukemia-associated antigens, to determine whether imminent relapse could be detected in patients with acute leukemia. Of 26 patients who relapsed by standard morphologic criteria, 21 had increased immunoreactivity of bone marrow for one to six months (mean, 3.7 months) before relapse. High concordance was observed between a positive test and relapse during the period of study (chi-square = 27.53, P
From The New England Journal of Medicine, Baker, M.A., Falk, J.A., Carter W.H., et al., Early Diagnosis of Relapse in Acute Myeloblastic Leukemia — Serologic Detection of Leukemia-Associated Antigens in Human Marrow, Vol. 301, Page 1353, Copyright © 1979 Massachusetts Medical Society. Reprinted with permission.
Is Part Of
VCU Internal Medicine Publications