DOI
https://doi.org/10.25772/TQVX-JT32
Defense Date
1980
Document Type
Thesis
Degree Name
Master of Science
Department
Biology
First Advisor
Loren G. Martin
Abstract
Clinical and experimental data suggest that humans and some animals are protected from acute myocardial infarction by estrogen. There has been much speculation of the exact role which estrogen plays in the circulation. The mechanism of this hormonally related protection is unclear.
In the present study the chronic effects of estradiol benzoate on coronary blood flow in adult female rats were studied. Female control rats, castrates and castrates receiving estrogen for a period of 16 weeks were used. In vivo tracer microsphere studies of myocardial blood flow allowed the quantification of the effects of estrogen on coronary circulation. Results of this work demonstrated that levels of estrogen significantly influence blood flow in ventricular myocardium.
Rights
© The Author
Is Part Of
VCU University Archives
Is Part Of
VCU Theses and Dissertations
Date of Submission
6-28-2016