DOI
https://doi.org/10.25772/A1AN-XM60
Defense Date
2018
Document Type
Thesis
Degree Name
Master of Science in Dentistry
Department
Dentistry
First Advisor
William Dahlke Jr. DMD
Second Advisor
Ross Belvin MS PhD
Third Advisor
Janina Lewis MS PhD
Fourth Advisor
Caroline Carrico PhD
Abstract
A COMPARISON OF THE ANTIMICROBIAL EFFICACY OF SILVER DIAMINE FLUORIDE AND SILVER NITRATE: AN IN VITRO STUDY
By: Nicholas L Luke, D.D.S.
A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Dentistry at Virginia Commonwealth University.
Virginia Commonwealth University, May 2018
Thesis Advisor: William O. Dahlke Jr., D.M.D.
Pediatric Dentistry, Department Chair
Purpose: To determine the antimicrobial efficacy of SDF and SN/NaF.
Methods: Three bacterial species were combined to create an in vitro biofilm. Treatment was completed with SN, SN/NaF, SDF, SDF½ or untreated (control).
Results: The untreated group demonstrated significantly higher growth than all other treatment groups across the study. On the BHI-plates (1-day), there were significant differences between all treatments except SDF and SDF½. On the BHI-plates (3-days), SN/NaF was not significantly different from SDF or SDF½. On the L-MRS-plates (1-day), both SN treatment groups yielded significantly higher growth than the SDF groups. On the L-MRS-plates (3-days), SN yielded significantly higher growth than SN/NaF, SDF, and SDF½.
Conclusion: SDF is more effective than SN/NaF, with the exception of BHI-plates (3-days) only and SN/NaF is more effective than SN on primarily S. mutans and L. acidophilus. There is evidence of a possible antimicrobial tolerance of oral bacteria to silver.
Rights
© The Author
Is Part Of
VCU University Archives
Is Part Of
VCU Theses and Dissertations
Date of Submission
4-23-2018