DOI

https://doi.org/10.25772/89T1-3X75

Defense Date

2023

Document Type

Dissertation

Degree Name

Doctor of Philosophy

Department

Biostatistics

First Advisor

Robert Perera

Abstract

In 2015, Open Science Framework directly replicated 100 psychology studies and found astonishingly low replication rates. Since, researchers have suggested factors that may have influenced the low rates, including the metrics used to assess replications. The definitions used to decide whether a replication study was successful all suffer from flaws. Therefore, we propose a new metric for assessing replication that can estimate the likelihood a study successfully replicated rather than forcing a binary choice and accounts for study design limitations.

Using equivalence study techniques, we first propose a new metric to assess replication, defining a successful replication as one where either the replicated study’s effect size or difference in the original or replicated effect size falls within the preset equivalence margin. We then compare our metric to current metrics using the Reproducibility Project data. Following this, we extend this approach to multiple studies using multivariate methods. Lastly, we design a survey to assess replication qualitatively.

We found, when assessing replication on a continuous scale more information on a study’s probability of replication is provided. Additionally, a study’s probability of replication is highly impacted by the study’s design elements such as sample size. When extending the equivalence metric to multiple studies, the replication probabilities decreased as the variance between studies played a larger role.

Using equivalence studies to assess replication allows replication success to fall on a continuous scale providing more information while having the ability to assess the impact study’s design elements have on replication rates.

Keywords: Replication, Underpowered Studies, Publication Bias, Equivalence Studies

Rights

© The Author

Is Part Of

VCU University Archives

Is Part Of

VCU Theses and Dissertations

Date of Submission

8-2-2023

Available for download on Thursday, August 01, 2024

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