"NeuroD1 AAV-Based Gene Therapy for Functional Brain Repair after Ische" by Marlena Ramlatchan
 

Document Type

Article Presentation

Original Publication Date

2022

Date of Submission

January 2023

Abstract

This study uses AAV based gene therapy to create an astrocyte- neuron conversion to regain functional abilities damaged by ischemic injuries. NeuroD1 treatment has shown promising results in the treatment of ischemic injuries in rodents and is heading towards clinical trials. Cognitive and motor improvements were shown. The basis of this therapy is to use functional glial cells to promote neurocellular growth, which would restore some function lost as a result of injury.

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© The Author(s)

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