Document Type

Article

Original Publication Date

2010

Journal/Book/Conference Title

Journal of Applied Physics

Volume

107

Issue

6

DOI of Original Publication

10.1063/1.3359656

Comments

Originally published at http://dx.doi.org/10.1063/1.3359656

Date of Submission

October 2015

Abstract

We investigated the laser-induced fluorescence of particles of a compound thermographic phosphorLa2O2S:Eu(1%) and Gd2O2S:Eu(1%) to see if they can serve as a surrogate for cells transfected with the green fluorescent protein, in tests of neurocatheters used for intraparenchymal celldelivery. At an excitation wavelength of 337 nm and a concentration of ≈2×106 particles ml−1, the resulting slurries produced fluorescence intensities at 625 nm that were within a factor of 2 of those produced by similar number densities of relevant cells, thus suggesting the utility of this approach.

Rights

Allison, S. W., and Gillies, G. T. Dual-doped thermographic phosphor particles as surrogates for green fluorescent protein-labeled cells in tests of cytometric neurocatheters. Journal of Applied Physics, 107, 064904 (2010). Copyright © 2010 American Institute of Physics.

Is Part Of

VCU Neurosurgery Publications

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