Document Type
Article
Original Publication Date
2015
Journal/Book/Conference Title
Bone & Joint Research
Volume
4
DOI of Original Publication
10.1302/2046-3758.43.2000337
Date of Submission
May 2016
Abstract
Objectives The clinical utility of routine cross sectional imaging of the abdomen and pelvis in the screening and surveillance of patients with primary soft-tissue sarcoma of the extremities for metastatic disease is controversial, based on its questionable yield paired with concerns regarding the risks of radiation exposure, cost, and morbidity resulting from false positive findings.
Methods Through retrospective review of 140 patients of all ages (mean 53 years; 2 to 88) diagnosed with soft-tissue sarcoma of the extremity with a mean follow-up of 33 months (0 to 291), we sought to determine the overall incidence of isolated abdominopelvic metastases, their temporal relationship to chest involvement, the rate of false positives, and to identify disparate rates of metastases based on sarcoma subtype.
Results A total of four patients (2.9%) exhibited isolated abdominopelvic metastatic disease during the surveillance period. In all cases of concomitant chest and abdominopelvic disease, chest involvement preceded abominopelvic involvement. There was a significant false positive rate requiring invasive workup.
Conclusions In the setting of a relative paucity of evidence concerning a rare disease process and in difference to recently published investigations, we add a clinical cohort not supportive of routine cross sectional imaging of the abdomen and pelvis.
Rights
Copyright ©2015 The British Editorial Society of Bone & Joint Surgery
Is Part Of
VCU Orthopaedic Surgery Publications
Comments
Originally published at http://dx.doi.org/10.1302/2046-3758.43.2000337