Publications from the Department of Physiology and Biophysics, Virginia Commonwealth University.

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Submissions from 2013

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S3-S4 Linker Length Modulates the Relaxed State of a Voltage-Gated Potassium Channel, Michael F. Priest, Jérôme J. Lacroix, Carlos A. Villalba-Galea, and Fancisco Bezanilla

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In Vivo Regulation of Brain-Derived Neurotrophic Factor in Dorsal Root Ganglia Is Mediated by Nerve Growth Factor-Triggered Akt Activation during Cystitis, Li-Ya Qiao, Sharon Yu, Jarren C. Kay, and Chun-mei Xia

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Distinctive G Protein-Dependent Signaling by Protease-Activated Receptor 2 (PAR2) in Smooth Muscle: Feedback Inhibition of RhoA by cAMP-Independent PKA, Wimolpak Sriwai, Sunila Mahavadi, Othman Al-Shboul, John R. Grider, and Karnam S. Murthy

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Building KCNQ1/KCNE1 Channel Models and Probing their Interactions by Molecular-Dynamics Simulations, Yu Xu, Yuhong Wang, Xuan-Yu Meng, Mei Zhang, Min Jiang, Meng Cui, and Gea-Ny Tseng

Submissions from 2012

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Normal-Mode-Analysis-Guided Investigation of Crucial Intersubunit Contacts in the cAMP-Dependent Gating in HCN Channels, Farzana Marni, Shengjun Wu, Gaurav M. Shah, Xin-ping Xu, Amber R. Hackett, Changan Xie, Sabisha Shrestha, Lin Liu, Qinglian Liu, and Lei Zhou

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Predicting Protein Interactions by Brownian Dynamics Simulations, Xuan-Yu Meng, Yu Xu, Hong Zhang, Mihaly Mezei, and Meng Cui

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The Molecular Mechanism by which PIP2 Opens the Intracellular G-Loop Gate of a Kir3.1 Channel, Xuan-Yu Meng, Hong-Xing Zhang, Diomedes E. Logothetis, and Meng Cui

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Staphylococcus aureus and Escherichia coli have disparate dependences on KsgA for growth and ribosome biogenesis, Heather Colleen O'Farrell and Jason P. Rife

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A Blue Native-PAGE analysis of membrane protein complexes in Clostridium thermocellum, Yanfeng Peng, Yuanming Luo, Tingting Yu, Xinping Xu, Keqiang Fan, Youbao Zhao, and Kequian Yang

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FRET-Based Localization of Fluorescent Protein Insertions Within the Ryanodine Receptor Type 1, Shweta A. Raina, Jeffrey Tsai, Montserrat Samsó, and James D. Fessenden

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Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat, Chun-mei Xia, Melisa A. Gulick, Sharon Yu, John R. Grider, Karnam S. Murthy, John K. Kuemmerle, and Hamid I. Akbarali

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Activation of extracellular signal-regulated protein kinase 5 is essential for cystitis- and nerve growth factor-induced calcitonin gene-related peptide expression in sensory neurons, Sharon Yu, Chun-mei Xia, and Li-Ya Qiao

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The Interdomain Linker of AAV-2 Rep68 Is an Integral Part of Its Oligomerization Domain: Role of a Conserved SF3 Helicase Residue in Oligomerization, Francisco Zarate-Perez, Martino Bardelli, John W. Burgner II, Maria Villamil-Jarauta, Kanni Das, Demet Kekilli, Jorge Mansilla-Soto, R. Michael Linden, and Carlos R. Escalante

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MEKK1-MKK4-JNK-AP1 Pathway Negatively Regulates Rgs4 Expression in Colonic Smooth Muscle Cells, Yonggang Zhang, Fang Li, Shu Liu, Hong Wang, Sunila Mahavadi, Karnam S. Murthy, Kamel Khalili, and Wenhui Hu

Submissions from 2011

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3D Mapping of the SPRY2 Domain of Ryanodine Receptor 1 by Single-Particle Cryo-EM, Alex Peralvaerz-Marin, HanShen Tae, Phillip G. Board, Marco G. Casarotto, Angela F. Dulhunty, and Montserrat Samsó

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Cholesterol Sensitivity of KIR2.1 Is Controlled by a Belt of Residues around the Cytosolic Pore, Avia Rosenhouse-Dantsker, Diomedes E. Logothetis, and Irena Levitan

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State-Dependent cAMP Binding to Functioning HCN Channels Studied by Patch-Clamp Fluorometry, Shengjun Wu, Zhanna V. Vysotskaya, Xinping Xu, Changan Xie, Qinglian Liu, and Lei Zhou

Submissions from 2010

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An analytical tool for elucidating ion-channel molecular mechanisms from macroscopic current traces, Miguel Fribourg, Belen Galocha-Iraguen, Fernando Las Heras-Andres, Diomedes E. Logothetis, and Vladimir Brezina

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A Molecular Dynamics Investigation of Lipid Bilayer Perturbation by PIP2, Dmitry Lupyan, Mihaly Mezei, Diomedes E. Logothetis, and Roman Osman

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Long-Term Fish Oil Supplementation Induces Cardiac Electrical Remodeling by Changing Channel Protein Expression in the Rabbit Model, Xulin Xu, Min Jiang, Yuhong Wang, Timothy Smith, Clive M. Baumgarten, Mark A. Wood, and Gea-Ny Tseng

Submissions from 2009

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DNA Structure Modulates the Oligomerization Properties of the AAV Initiator Protein Rep68, Jorge Mansilla-Soto, Miran Yoon-Robarts, William J. Rice, Shailee Arya, Carlos R. Escalante, and R. Michael Linden

Submissions from 2007

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Probing the Outer Mouth Structure of the hERG Channel with Peptide Toxin Footprinting and Molecular Modeling, Gea-Ny Tseng, Kailas D. Sonawane, Yuliya V. Korolkova, Mei Zhang, Jie Liu, Eugene V. Grishin, and H. Robert Guy

Submissions from 2003

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BeKm-1 Is a HERG-Specific Toxin that Shares the Structure with ChTx but the Mechanism of Action with ErgTx1, Mei Zhang, Yuliya V. Korolkova, Jie Liu, Min Jiang, Eugene V. Grishin, and Gea-Ny Tseng

Submissions from 1997

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Analysis of phosphorescence in heterogeneous systems using distributions of quencher concentration, A.S. Golub, A.S. Popel, L. Zheng, and R.N. Pittman

Submissions from 1989

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Direct measurement of translingual epithelial NaCl and KCl currents during the chorda tympani taste response, G. L. Heck, K. C. Persaud, and J. A. DeSimone