Spit for Science Publications and Presentations
Document Type
Presentation
Original Publication Date
2022
Date of Submission
January 2025
Abstract
This study examines the consequences of Alzheimer’s in rat and mice test subjects. The goal is to identify the effects of certain NLRP3 inhibiting drugs and to see if there are any noticeable effects in regards to impeding the pathological development of Alzheimer’s disease. The results are visualized by implementing the immunohistochemical process to identify neurodegeneration in the brain and to assess the expression levels of amyloid beta as an indicator of Alzheimer’s pathology. Other tests are also conducted on these transgenic mice to gauge cognitive functioning levels during the onset of their disease, those being behavior tests, but not limited to the extraction of information on the results of the NLRP3 inhibitor drug trials which aid in adding to the existing database of quantitative data from previous tests. The results of this study play into further understanding of this crippling neurodegenerative disease.
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Spit for Science Publications and Presentations