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Original Publication Date
2018
Document Type
Presentation
Abstract
Sana Hosseini’s research focuses on developing safer and more effective targeted drug delivery systems for respiratory diseases such as rhinosinusitis and obstructive sleep apnea, which affect nearly one in five U.S. adults. The respiratory tract offers a promising, noninvasive route for drug administration, allowing medications to be absorbed quickly through the mucous membranes into the bloodstream. However, current systemic drug delivery methods can pose serious side effects—especially in pediatric patients, whose airway structures differ significantly from adults. To address these challenges, Hosseini is designing engineered delivery techniques that precisely target therapeutic sites within the respiratory system. Her research employs artificial airway models created with 3D printing technology to study pharmacological and toxicological effects in controlled environments, advancing the development of safe, efficient, and age-appropriate inhaled drug delivery methods.
Transcription
According to C.D.C. Centers for Drug Control and Prevention up to 12 percent of U.S. adult population are suffering from rhinosinusitis or simply sinus infection. About 7 percent are struggling with obstructive sleep apnea. Before event talk recalling any other stats or talking about compelling needs on cancer techniques I would say those two numbers are quite concerning for us as engineers to get hands on developing and designing drug delivery techniques. Your respiratory track has been built on as a safe and non invasive route for a variety after therapeutics while being metabolism assimilated drug could get. Could get absorbed quicker across the mucus membrane into the blood stream. Now granted increasing amount of research are being done on systemic drug delivery to denotes. Well yet many questions remain concerning whether those are still effective enough for younger ages or not, apparently not though. Since health side, potential health side effects of systemic drug delivery is quite critical for pediatrics plus the fact that morphology of the air base is quite different for younger ages compared to the adults. Knowing all these challenges so my research is a mean to carry therapeutics to target it cites of delivery in respiratory track well when it comes to testing constituting toxicology out pharmacology aspects it's not quite or smart or even physical. Playing with science or trial and error straight on human body because so that's the reason so we are experimenting in. Artificial environments or basically our 2 D. printer realistic air models to develop our techniques and devices for targeted drug delivery. Thank you for your time.
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Comments
Entrant, 4th Annual VCU 3MT® Competition, held on October 18-19, 2018.