Proximity ligation assays: A powerful technique to detect protein-protein interactions and histone modifications [online video]

Document Type

Presentation

Original Publication Date

2017

Streaming Media

Comments

An instructional brown-bag lunch talk for the general VCU health sciences community, given on November 13, 2017.

Date of Submission

November 2017

Abstract

Proximity ligation assay (PLA) has become the assay of choice for demonstrating the proximity of a variety of proteins, including G Protein-Coupled Receptors (GPCRs), in cells and native tissue. Recently, this technique has been applied in native tissue to detect histone modifications in certain promoters, increasing the information (specific cells carrying the modifications) obtained by doing ChiP.

Rights

© The Author

Is Part Of

VCU How-To Talks by Postdocs

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