Submissions from 2019
Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation, Shravan Morla
Submissions from 2018
Kinetics and Inhibition Studies of the L205R Mutant of cAMP-Dependent Protein Kinase Involved in Cushing’s Syndrome, Nicole M. Luzi, Charles E. Lyons, Darrell L. Peterson, and Keith C. Ellis
Submissions from 2017
The anti-sepsis activity of the components of Huanglian Jiedu Decoction with high lipid A-binding affinity, Guirong Chen, Yubin Xu, Jing Jing, Brianna Mackie, Xinchuan Zheng, Xu Zhang, Jing Wang, and Xuetao Li
Submissions from 2016
Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile, Rami A. Al-Horani, Rajesh Karuturi, Michael Lee, Daniel K. Afosa, and Umesh R. Desai
Exploration of bivalent ligands targeting putative mu opioid receptor and chemokine receptor CCR5 dimerization, Christopher K. Arnatt, Bethany A. Falls, Yunyun Yuan, Thomas J. Raborg, Ruturaj R. Masvekar, Nazira El-Hage, Dana E. Selley, Anthony V. Nicola, Pamela E. Knapp, Kurt F. Hauser, and Yan Zhang
Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes, Zhongnv Ma, Xianbao Shi, Gang Zhang, Feng Guo, Lina Shan, and Jiqun Cai
Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes, Zhongnv Ma, Xianbao Shi, Gang Zhang, Feng Guo, Lina Shan, and Jiqun Cai
Submissions from 2015
Plasmin Regulation through Allosteric, Sulfated, Small Molecules, Rami A. Al-Horani, Rajesh Karuturi, Domonique T. White, and Umesh R. Desai
Structural Studies of AAV2 Rep68 Reveal a Partially Structured Linker and Compact Domain Conformation, Faik N. Musayev, Francisco Zarate-Perez, Martino Bardelli, Clayton Bishop, Emil F. Saniev, R. Michael Linden, Els Henckaerts, and Carlos R. Escalante
A Simple Method for Discovering Druggable, Specific Glycosaminoglycan-Protein Systems. Elucidation of Key Principles from Heparin/Heparan Sulfate-Binding Proteins, Aurijit Sarkar and Umesh R. Desai
6-Hydroxyflavone and Derivatives Exhibit Potent Anti-Inflammatory Activity among Mono-, Di- and Polyhydroxylated Flavones in Kidney Mesangial Cells, Xing Wang, Zhiwei Wang, Preetpal Singh Sidhu, Umesh R. Desai, and Qibing Zhou
Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways, Qiong Wei, Haijuan Liu, Honghao Zhou, Dejun Zhang, Zhiwei Zhang, and Qibing Zhou
Submissions from 2014
Intuitive, But Not Simple: Including Explicit Water Molecules in Protein-Protein Docking Simulations Improves Model Quality, Hardik I. Parikh and Glen E. Kellogg
Crystal Structures of Influenza A Virus Matrix Protein M1: Variations on a Theme, Martin K. Safo, Faik N. Musayev, Philip D. Mosier, Qibing Zhou, Hang Xie, and Umesh R. Desai
Toward a robust computational screening strategy for identifying glycosaminoglycan sequences that display high specificity for target proteins, Nehru Viji Sankaranarayanan and Umesh R. Desai
Comparison of the Inhibitory Potential of Bavachalcone and Corylin against UDP-Glucuronosyltransferases, Lina Shan, Shuman Yang, Gang Zhang, Dun Zhou, Zhenyu Qiu, Lei Tian, Hongxia Yuan, Yujun Feng, and Xianbao Shi
Submissions from 2013
Biological Characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a Selective Sphingosine Kinase-2 Inhibitor and Anticancer Agent, Kai Liu, Tai L. Guo, Nitai C. Hait, Jeremy Allegood, Hardik I. Parikh, Wenfang Xu, Glen E. Kellogg, Steven Grant, Sarah Spiegel, and Shijun Zhang
Cyanine 5.5 Conjugated Nanobubbles as a Tumor Selective Contrast Agent for Dual Ultrasound-Fluorescence Imaging in a Mouse Model, Liyi Mai, Anna Yao, Jing Li, Qiong Wei, Ming Yuchi, Xiaoling He, Mingyue Ding, and Qibing Zhou
Isozyme-Specific Ligands for O-acetylserine sulfhydrylase, a Novel Antibiotic Target, Francesca Spyrakis, Ratna Singh, Pietro Cozzini, Enea Salsi, Paolo Felici, Samanta Raboni, Paolo Benedetti, Gabriele Cruciani, Glen E. Kellogg, Paul F. Cook, and Andrea Mozzarelli
Submissions from 2012
A GGA plus U approach to effective electronic correlations in thiolate-ligated iron-oxo (IV) porphyrin, Justin Elenewski and John C. Hackett
Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition, Amit Gandhi, Jigar V. Desai, Mohini S. Ghatge, Martino L. di Salvo, Stefano Di Biase, Richmond Danso-Danquah, Faik N. Musayev, Roberto Contestabile, Verne Schirch, and Martin A. Safo
Pyridoxal 5′-Phosphate Is a Slow Tight Binding Inhibitor of E. coli Pyridoxal Kinase, Mohini S. Ghatge, Roberto Contestabile, Martino L. di Salvo, Jigar V. Desai, Amit Gandhi, Christina M. Camara, Rita Florio, Isabel N. Gonzalez, Alessia Parroni, Verne Schirch, and Martin A. Safo
On the Specificity of Heparin/Heparan Sulfate Binding to Proteins. Anion-Binding Sites on Antithrombin and Thrombin Are Fundamentally Different, Philip D. Mosier, Chandravel Krishnasamy, Glen E. Kellogg, and Umesh R. Desai
Design, Synthesis, and In Vitro and In Vivo Biological Studies of a 3′-Deoxythymidine Conjugate that Potentially Kills Cancer Cells Selectively, Qiong Wei, Dejun Zhang, Anna Yao, Liyi Mai, Zhiwei Zhang, and Qibing Zhou
Submissions from 2011
Bound Water at Protein-Protein Interfaces: Partners, Roles and Hydrophobic Bubbles as a Conserved Motif, Mostafa H. Ahmed, Francesca Spyrakis, Pietro Cozzini, Parijat K. Tripathi, Andrea Mozzarelli, J. Neel Scarsdale, Martin A. Safo, and Glen E. Kellogg