Document Type
Article Presentation
Original Publication Date
2024
Date of Submission
March 2025
Abstract
This presentation focuses on the development of the Small Airway-on-a-Chip, a microfluidic device meant to serve as a more accurate, human-relevant research model for lung inflammation-focused pharmaceutical testing, as described in Small Airway-on-a-Chip Enables Analysis of Human Lung Inflammation and Drug Responses in Vitro by Benam et al. Currently, there is no way to study organ-level complexities of human lung inflammation outside of the clinical setting. However, the human lung Small Airway-on-a-Chip demonstrated the ability to reconstitute a functional unit of the lung as well as model asthma, lung inflammation, and Chronic Obstructive Pulmonary Disease (COPD), suggesting that the device may hold significant potential for enhancing pharmaceutical research in the future.
Rights
© The Author(s)
