Document Type

Article

Original Publication Date

2017

Volume

47

Issue

3

DOI of Original Publication

10.1007/s10519-016-9833-z

Comments

Originally published at https://doi.org/10.1007/s10519-016-9833-z

Date of Submission

June 2017

Abstract

Results from previous studies on DSM-IV and DSM-5 Antisocial Personality Disorder (ASPD) have suggested that the construct is etiologically multidimensional. To our knowledge, however, the structure of genetic and environmental influences in ASPD has not been examined using an appropriate range of biometric models and diagnostic interviews. The 7 ASPD criteria (section A) were assessed in a population-based sample of 2794 Norwegian twins by a structured interview for DSM-IV personality disorders. Exploratory analyses were conducted at the phenotypic level. Multivariate biometric models, including both independent and common pathways, were compared. A single phenotypic factor was found, and the best-fitting biometric model was a single-factor common pathway model, with common-factor heritability of 51% (95% CI 40–67%). In other words, both genetic and environmental correlations between the ASPD criteria could be accounted for by a single common latent variable. The findings support the validity of ASPD as a unidimensional diagnostic construct.

Rights

© Springer Science+Business Media New York 2017

Is Part Of

VCU Psychiatry Publications

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